Leveraging the discovery of transglutaminase-mediated immunodominance (https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2023021335), Tree of Life Biologics INC. provides novel and proprietary artificial intelligence and biochip-based epitope mapping and immunogen design services and products for the development of vaccines and pe
Leveraging the discovery of transglutaminase-mediated immunodominance (https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2023021335), Tree of Life Biologics INC. provides novel and proprietary artificial intelligence and biochip-based epitope mapping and immunogen design services and products for the development of vaccines and peptides aiming to prevent and treat most life-threatening diseases today.
We perform cost-efficient epitope identification algorithms and high-throughput protein array-based immunogen screening campaign to determine the immunodominant epitopes and their variants in any target protein of any disease.
Our platform for immunogen determination and optimization is a technology evolving epitope design. First, the epitope candidates would induce both humoral and T cell responses. Second, our approach could optimize the epitope motif into a more immunoreactive variant. Third, introduction of glutamine residues is able to create immunogenicity for a peptide.